AIDS, loss and renewal

RENEWAL Ethiopia Background Paper: HIV/AIDS, Food and Nutrition Security

Precursor loss triggers AIDS

In the MyD88 family of cytosolic adaptor proteins, the newest member is the group's black sheep, according to Kim et al. (page 2063). Whereas most MyD88 proteins turn on anti-pathogen responses within myeloid cells, the rebel, MyD88-5, instigates cell death within neurons. MyD88-1–4 all respond to Toll-like receptor (TLR) activation in leuko-cytes and stimulate innate immune responses. MyD88-5,...

Stigma Regarding Hearing Loss and Hearing Aids

Stigma regarding hearing loss and hearing aids presents a great challenge, especially because dealing with its consequences in an appropriate and timely manner might be associated with better outcomes for the person with hearing loss, their caregivers, and society. A clear understanding of the stigma concept and its measurement in the area of hearing loss among older adults might advance knowle...

Disc loss and renewal in A 0535 + 26

This paper presents observations of the Be/X-ray binary system A0535+26 revealing the first observed loss of its circumstellar disc, demonstrated by the loss of its JHK infrared excess and optical/IR line emission. However optical/IR spectroscopy reveals the formation of a new inner disc with significant density and emission strength at small radii; the disc has proven to be stable over 5 month...

Loss of Hematopoietic Stem Cell Self - Renewal After Bone Marrow

The quality of long-term hematopoietic engraftment after bone marrow transplantation (BMT) has not been well characterized. Clinical autologous BMT involves removal of <5% of the total content of the recipient marrow followed by ablation of the remaining marrow and reinfusion. To study long-term consequences of transplanting limited numbers of BM stem cells further, we evaluated the hematopoiet...